Classification of form under heterogeneity and non-isotropic errors

A number of areas related to learning under supervision have not been fully investigated, particularly the possibility of incorporating the method of classification into shape analysis. In this regard, practical ideas conducive to the improvement of form classification are the focus of interest. Our proposal is to employ a hybrid classifier built on Euclidean Distance Matrix Analysis (EDMA) and Procrustes distance, rather than generalised Procrustes analysis (GPA). In empirical terms, it has been demonstrated that there is notable difference between the estimated form and the true form when EDMA is used as the basis for computation. However, this does not seem to be the case when GPA is employed. With the assumption that no association exists between landmarks, EDMA and GPA are used to calculate the mean form and diagonal weighting matrix to build superimposing classifiers. As our findings indicate, with the use of EDMA estimators, the superimposing classifiers we propose work extremely well, as opposed to the use of GPA, as far as both simulated and real datasets are concerned

LakeCC: a tool for efficiently identifying lake basins with application to palaeogeographic reconstructions of North America

Along the margins of continental ice sheets, lakes formed in isostatically depressed basins duringglacial retreat. Their shorelines and extent are sensitive to the ice margin and the glacial history of the region.Proglacial lakes, in turn, also impact the glacial isostatic adjustment due to loading, and ice dynamics by posing amarine‐like boundary condition at the ice margin. In this study we present a tool that efficiently identifies lake basinsand the corresponding maximum water level for a given ice sheet and topography reconstruction. This algorithm,called the LakeCC model, iteratively checks the whole map for a set of increasing water levels and fills isolated basinsuntil they overflow into the ocean. We apply it to the present‐day Great Lakes and the results show good agreement(∼1−4%) with measured lake volume and depth. We then apply it to two topography reconstructions of NorthAmerica between the Last Glacial Maximum and the present. The model successfully reconstructs glacial lakes suchas Lake Agassiz, Lake McConnell and the predecessors of the Great Lakes. LakeCC can be used to judge the quality ofice sheet reconstructions

Speculative devices for photo display

In this paper, we describe three purposefully provocative, digital photo display technologies designed for home settings. The three devices have been built to provoke questions around how digital photographs might be seen and interacted with in novel ways. They are also intended for speculation about the expressive resources afforded by digital technologies for displaying photos. It is hoped interactions with the devices will help researchers and designers reflect on new design possibilities. The devices are also being deployed as part of ongoing home-oriented field research

White matter integrity as a predictor of response to treatment in first episode psychosis

The integrity of brain white matter connections is central to a patient's ability to respond to pharmacological interventions. This study tested this hypothesis using a specific measure of white matter integrity, and examining its relationship to treatment response using a prospective design in patients within their first episode of psychosis. Diffusion tensor imaging data were acquired in 63 patients with first episode psychosis and 52 healthy control subjects (baseline). Response was assessed after 12 weeks and patients were classified as responders or non-responders according to treatment outcome. At this second time-point, they also underwent a second diffusion tensor imaging scan. Tract-based spatial statistics were used to assess fractional anisotropy as a marker of white matter integrity. At baseline, non-responders showed lower fractional anisotropy than both responders and healthy control subjects (P < 0.05; family-wise error-corrected), mainly in the uncinate, cingulum and corpus callosum, whereas responders were indistinguishable from healthy control subjects. After 12 weeks, there was an increase in fractional anisotropy in both responders and non-responders, positively correlated with antipsychotic exposure. This represents one of the largest, controlled investigations of white matter integrity and response to antipsychotic treatment early in psychosis. These data, together with earlier findings on cortical grey matter, suggest that grey and white matter integrity at the start of treatment is an important moderator of response to antipsychotics. These findings can inform patient stratification to anticipate care needs, and raise the possibility that antipsychotics may restore white matter integrity as part of the therapeutic response

A review of the evolution of robotic-assisted total hip arthroplasty.

INTRODUCTION: Total hip arthroplasty (THA) is currently a very successful operation but continues to evolve as we try to perfect techniques and improve outcomes for our patients. Robotic hip surgery (RHS) began with the 'active' ROBODOC system in the 1980s. There were drawbacks associated with the original ROBODOC and most recently, the MAKO robot was introduced with early promising results. AIM: The aim of this paper is to provide an up-to-date review surrounding this area and discuss the pros and cons of this technique. METHODS: A literature review searching Medline, Embase, Ovidsp, Cochrane library, pubmed database and google scholar was performed searching keywords including: 'Robotic hip surgery', 'Robotic orthopaedic surgery', 'Computer assisted hip surgery', 'robotic arthroplasty', and 'computer assisted orthopaedic surgery'. CONCLUSION: Robotic hip surgery aims to tackle the limitations of the human factor in surgery by promising reproducible and reliable methods of component positioning in arthroplasty surgery. However, as orthopaedic surgeons, we must critically appraise all new technology and support the use providing there is sound robust evidence backing it

Recent studies of cements and concretes by synchrotron radiation crystallographic and cognate methods

The portfolio of available synchrotron radiation techniques is increasing notably for cements and pastes. Furthermore, sometimes the terminology is confusing and an overall picture highlighting similarities and differences of related techniques was lacking. Therefore, the main objective of this work is to review recent advances in synchrotron techniques providing a comprehensive overview. This work is not intended to gather all publications in cement chemistry but to give a unified picture through selected examples. Crystallographic techniques are used for structure determination, quantitative phase analyses and microstructure characterization. These studies are not only carried out in standard conditions but synchrotron techniques are especially suited to non-ambient conditions: high temperatures and pressures, hydration, etc., and combinations. Related crystallographic techniques, like Pair Distribution Function, are being used for the analysis of ill-crystalline phase(s). Furthermore, crystallographic tools are also employed in imaging techniques including scanning diffraction microscopy and tomography and coherent diffraction imaging. Other synchrotron techniques are also reviewed including X-rays absorption spectroscopy for local structure and speciation characterizations; small angle X-ray scattering for microstructure analysis and several imaging techniques for microstructure quantification: full-field soft and hard X-ray nano-tomographies; scanning infrared spectro-microscopy; scanning transmission and fluorescence X-ray tomographies. Finally, a personal outlook is provided.I am grateful to all my coauthors, collaborators, colleagues and PhD students, for all our work together during more than two decades. I thank the University of Malaga and ALBA Synchrotron Light Source for the support and the stirring environments. I acknowledge the Spanish science funding agencies (they change the name quite often) for funding my studentship, to do the PhD and the three summer research stays at Oxford University, to the last ongoing research project. To all synchrotrons I have been allowed to enjoy carrying out experiments: SRS, ESRF, Max-Lab, DLS, APS, SLS and ALBA. Finally, this work has been supported by the Spanish MINECO through the BIA2014-57658-C2-1-R research grant

Development of space vector modulation control schemes for grid connected variable speed permanent magnet synchronous generator wind turbines

This paper presents modelling, simulation and analysis of novel control strategies for variable speed wind turbines driven by a Permanent Magnet Synchronous Generators (PMSG) connected to the grid. The machine side controller is designed to match Maximum Power Point Tracking (MPPT) to obtain high extraction of wind power while connected to a the grid, and the grid side controller fixes the DC voltage that is converted to fixed 3-ph AC voltages and frequency. Main strategies of PI control and Model Predictive Control (MPC) have been discussed and compared to each other. Simulated voltage and current profiles are also presented in the paper in different cases of operation

A hybrid radiation detector for simultaneous spatial and temporal dosimetry

In this feasibility study an organic plastic scintillator is calibrated against ionisation chamber measurements and then embedded in a polymer gel dosimeter to obtain a quasi-4D experimental measurement of a radiation field. This hybrid dosimeter was irradiated with a linear accelerator, with temporal measurements of the dose rate being acquired by the scintillator and spatial measurements acquired with the gel dosimeter. The detectors employed in this work are radiologically equivalent; and we show that neither detector perturbs the intensity of the radiation field of the other. By employing these detectors in concert, spatial and temporal variations in the radiation intensity can now be detected and gel dosimeters can be calibrated for absolute dose from a single irradiation

Visualizing sound emission of elephant vocalizations: evidence for two rumble production types

Recent comparative data reveal that formant frequencies are cues to body size in animals, due to a close relationship between formant frequency spacing, vocal tract length and overall body size. Accordingly, intriguing morphological adaptations to elongate the vocal tract in order to lower formants occur in several species, with the size exaggeration hypothesis being proposed to justify most of these observations. While the elephant trunk is strongly implicated to account for the low formants of elephant rumbles, it is unknown whether elephants emit these vocalizations exclusively through the trunk, or whether the mouth is also involved in rumble production. In this study we used a sound visualization method (an acoustic camera) to record rumbles of five captive African elephants during spatial separation and subsequent bonding situations. Our results showed that the female elephants in our analysis produced two distinct types of rumble vocalizations based on vocal path differences: a nasally- and an orally-emitted rumble. Interestingly, nasal rumbles predominated during contact calling, whereas oral rumbles were mainly produced in bonding situations. In addition, nasal and oral rumbles varied considerably in their acoustic structure. In particular, the values of the first two formants reflected the estimated lengths of the vocal paths, corresponding to a vocal tract length of around 2 meters for nasal, and around 0.7 meters for oral rumbles. These results suggest that African elephants may be switching vocal paths to actively vary vocal tract length (with considerable variation in formants) according to context, and call for further research investigating the function of formant modulation in elephant vocalizations. Furthermore, by confirming the use of the elephant trunk in long distance rumble production, our findings provide an explanation for the extremely low formants in these calls, and may also indicate that formant lowering functions to increase call propagation distances in this species'